Georg F Hoffmann Selected Research

Histidine (L-Histidine)

7/2016	CNDP1 genotype and renal survival in pediatric nephropathies.
11/2015	Carnosine metabolism in diabetes is altered by reactive metabolites.
1/2011	Anserine inhibits carnosine degradation but in human serum carnosinase (CN1) is not correlated with histidine dipeptide concentration.

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Georg F Hoffmann Research Topics

Disease

19	Phenylketonurias (Phenylketonuria) 10/2021 - 03/2002
12	Propionic Acidemia 04/2024 - 10/2004
11	Brain Diseases (Brain Disorder) 01/2022 - 01/2003
10	Inborn Urea Cycle Disorders 12/2023 - 09/2005
9	Methylmalonic acidemia 04/2024 - 04/2002
9	Metabolic Diseases (Metabolic Disease) 01/2024 - 07/2002
8	Dystonia (Limb Dystonia) 08/2017 - 07/2002
7	Seizures (Absence Seizure) 01/2019 - 02/2003
7	Inborn Errors Metabolism (Inborn Errors of Metabolism) 09/2017 - 11/2002
6	Homocystinuria 04/2024 - 09/2007
6	Vitamin B 12 Deficiency (Vitamin B12 Deficiency) 07/2023 - 04/2017
6	Intellectual Disability (Idiocy) 01/2019 - 12/2011
5	Aromatic amino acid decarboxylase deficiency 01/2024 - 03/2004
5	Cystic Fibrosis (Mucoviscidosis) 01/2024 - 10/2010
5	Hyperammonemia 11/2023 - 05/2011
5	Epilepsy (Aura) 10/2022 - 04/2005
5	Medium chain acyl CoA dehydrogenase deficiency 06/2022 - 10/2002
5	due to Sepiapterin Reductase Deficiency Dopa-Responsive Dystonia 11/2021 - 11/2006
5	Mevalonate Kinase Deficiency 01/2021 - 02/2003
5	Atrophy 01/2021 - 05/2002
5	Muscle Hypotonia (Hypotonia) 01/2021 - 01/2007
4	Citrullinemia 12/2023 - 09/2018
4	Mitochondrial Diseases (Mitochondrial Disease) 11/2023 - 08/2006
4	Multiple Acyl Coenzyme A Dehydrogenase Deficiency 11/2023 - 10/2008
4	Hypoglycemia (Reactive Hypoglycemia) 06/2022 - 10/2002
4	Neurodevelopmental Disorders 01/2022 - 03/2016
4	Movement Disorders (Movement Disorder) 01/2021 - 10/2004
4	B BH4-Deficient Hyperphenylalaninemia 09/2020 - 06/2011
4	Acute Liver Failure (Fulminant Hepatic Failure) 01/2019 - 01/2009
4	Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders) 01/2019 - 03/2002
4	Congenital Disorders of Glycosylation 01/2018 - 11/2010
3	Methylenetetrahydrofolate reductase deficiency 04/2024 - 10/2018
3	Ornithine Carbamoyltransferase Deficiency Disease 12/2023 - 09/2011
3	Infections 05/2023 - 01/2016
3	Fever (Fevers) 05/2023 - 06/2004
3	Nervous System Diseases (Neurological Disorders) 03/2021 - 04/2005
3	autosomal recessive Segawa syndrome 01/2021 - 01/2003
3	Diabetic Nephropathies (Diabetic Nephropathy) 07/2020 - 11/2015
3	Glutaric Acidemia I 01/2017 - 05/2002
3	Neoplasms (Cancer) 04/2016 - 04/2013
3	Cerebellar Ataxia (Dysmetria) 02/2016 - 02/2003
3	Dopa-responsive Dystonia 03/2013 - 10/2007
2	Argininosuccinic Aciduria 12/2023 - 01/2019
2	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 10/2021 - 01/2019
2	Folic Acid Deficiency (Folic Acid Deficiencies) 06/2021 - 09/2007
2	Cognitive Dysfunction 01/2021 - 01/2019
2	Liver Failure 11/2020 - 01/2020
2	Muscular Diseases (Myopathy) 10/2020 - 03/2002
2	6-pyruvoyl-tetrahydropterin synthase deficiency 09/2020 - 03/2008
2	Glycogen Storage Disease Type II (Pompe's Disease) 01/2020 - 08/2002
2	Gaucher Disease (Gaucher's Disease) 01/2020 - 09/2017
2	Guanidinoacetate methyltransferase deficiency 01/2020 - 02/2003
2	Globoid Cell Leukodystrophy (Krabbe Disease) 10/2019 - 09/2017
2	Tuberous Sclerosis (Bourneville's Disease) 01/2019 - 10/2016

Drug/Important Bio-Agent (IBA)

15	EnzymesIBA 12/2023 - 03/2002
12	Neurotransmitter Agents (Neurotransmitter)IBA 07/2023 - 01/2003
11	Proteins (Proteins, Gene)FDA Link 12/2023 - 02/2010
11	AcidsIBA 01/2013 - 04/2002
9	Phenylalanine Hydroxylase (Phenylalanine 4 Monooxygenase)IBA 09/2020 - 04/2003
8	Phenylalanine (L-Phenylalanine)FDA Link 10/2021 - 03/2002
7	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 04/2024 - 09/2007
7	Levodopa (L Dopa)FDA LinkGeneric 07/2023 - 07/2002
7	Fatty Acids (Saturated Fatty Acids)IBA 06/2022 - 10/2002
5	Dopamine (Intropin)FDA LinkGeneric 01/2024 - 07/2002
5	Serotonin (5 Hydroxytryptamine)IBA 01/2024 - 07/2002
5	Methylmalonic AcidIBA 01/2023 - 08/2007
5	CholesterolIBA 01/2021 - 02/2003
4	Oxidoreductases (Dehydrogenase)IBA 01/2024 - 04/2005
4	Carnitine (L-Carnitine)FDA LinkGeneric 11/2023 - 11/2002
4	6-pyruvoyltetrahydropterin synthase (PTPS)IBA 11/2021 - 03/2008
4	HomocysteineIBA 10/2020 - 03/2010
4	sapropterin (tetrahydrobiopterin)FDA Link 09/2020 - 03/2008
4	Coenzyme A (CoA)IBA 01/2019 - 10/2010
4	Vitamin D FDA LinkGeneric 10/2017 - 01/2009
4	Lysine (L-Lysine)FDA Link 01/2017 - 09/2012
3	CystathionineIBA 04/2024 - 01/2017
3	Pancreatitis-Associated ProteinsIBA 01/2024 - 10/2010
3	Amino Acyl-tRNA Synthetases (Aminoacyl-tRNA Synthetase)IBA 11/2023 - 08/2016
3	IronIBA 01/2022 - 10/2017
3	Amino Acids FDA Link 01/2020 - 06/2011
3	GlycoconjugatesIBA 01/2018 - 03/2012
3	Histidine (L-Histidine)FDA Link 07/2016 - 01/2011
3	DipeptidesIBA 07/2016 - 01/2011
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2024 - 01/2017
2	Epinephrine (Adrenaline)FDA LinkGeneric 01/2024 - 01/2017
2	CitrullineIBA 12/2023 - 11/2023
2	Arginine (L-Arginine)FDA Link 12/2023 - 09/2012
2	Argininosuccinate Synthase (Argininosuccinate Synthetase)IBA 11/2023 - 01/2019
2	Biomarkers (Surrogate Marker)IBA 11/2023 - 10/2021
2	Vitamin B 6IBA 07/2023 - 01/2017
2	Biogenic Amines (Biogenic Amine)IBA 07/2023 - 02/2004
2	Acyl-CoA Dehydrogenase (Medium-Chain Acyl-Coenzyme A Dehydrogenase)IBA 06/2022 - 10/2002
2	Aromatic-L-Amino-Acid DecarboxylasesIBA 01/2021 - 04/2015
2	Transaminases (Aminotransferases)IBA 11/2020 - 12/2017
2	Systemic carnitine deficiencyIBA 10/2020 - 10/2010
2	GTP Cyclohydrolase (GTP Cyclohydrolase I)IBA 09/2020 - 03/2013

Therapy/Procedure

17	Therapeutics 12/2023 - 11/2004
6	Liver Transplantation 12/2023 - 09/2005
2	Enzyme Replacement Therapy 01/2020 - 01/2019
2	Emergency Treatment 01/2019 - 01/2014